Hey all, I wanted to reach out about an issue I’ve been facing lately. I’ve noticed many discussions around Metformin focus on its use for PCOS, but what about those of us taking it for different reasons? I’ve been prescribed Metformin for a separate issue, and I’d love to connect with others in a similar situation. How has your experience been with Metformin outside of PCOS? Have you encountered any unique challenges or benefits? Let’s share and support each other on this journey!
I remember reading a study that suggested it may be beneficial, but unfortunately I can’t locate it at the moment. Personally, I didn’t experience any side effects aside from the first couple of days when adjusting to a new dose. My doctor assured me that if it became too uncomfortable, I could stop.
I don’t have high AMH or PCOS, but I am taking metformin as an add-on for my next egg retrieval. My RE prescribed it as it may help with my DOR and poor egg quality. There is limited evidence that it could also decrease endo inflammation. I’ve been taking 750 mg ER for 3 months now and have only experienced slow transit constipation as a side effect. I’ve also lost weight and improved my A1C. I take it with my pills after dinner.
I am taking metformin for reasons unrelated to PCOS, insulin resistance, or blood sugar issues. I use it for egg quality and inflammation control, which is not a common use for this medication. Despite having good blood sugar levels and regular ovulation on my own, I believe metformin played a significant role in helping me conceive naturally just three months after starting it. My doctors also believe that metformin helped reduce inflammation caused by a complex surgery I had just before conception, allowing me to have a successful pregnancy despite the extent of the surgery.
I have come across many stories here where women believe that this has helped them greatly! If I have to go through another egg retrieval, I will definitely consider asking for it. Plus, the potential weight loss benefits are something I wouldn’t mind, especially if I gain 10-20lbs during the process. I am 40 years old, have a good AMH level, no PCOS, but just transferred my last embryo (had a live birth in 21, then a miscarriage, and two failures in the last 8 months).
I have a similar question - has anyone been prescribed Metformin for PCOS without insulin resistance? I’m curious if it can help with endometrial receptivity before FET.
I was diagnosed with PCOS, but thankfully I don’t have high testosterone levels. I do experience all the other symptoms though. The insulin resistance improved after losing weight and having gastric bypass surgery before starting IVF. A study I came across suggested that having a BMI of 26 or higher, like myself, could improve IVF results. My clinic also mentioned that it could enhance egg quality for PCOS patients. They gradually increased my dosage of medication and I did face some digestion issues initially. However, I have been taking it consistently for the past 2 years during my IVF journey.
Metformin is believed to have anti-aging benefits and has been studied as a drug that could benefit everyone by lowering sugar levels to reduce inflammation. It is seen as harmless and potentially beneficial.
I am in agreement with you. I am 38 years old with an AMH level of 0.295. I have been taking metformin since the beginning of my fertility journey. Despite not having any PCOS symptoms and having regular cycles, my doctor has recommended testing my egg quality and AMH levels. I am feeling very anxious about the results of this cycle. Last year, I tried Ovasitol and Ino from Theralogix, but it did not help much as only 2 eggs were retrieved. I would appreciate any prayers and support from fellow women. <3
Consult with your physician regarding trying Myo-Inositol as an alternative option. It provides similar benefits without the associated side effects. Although I have not personally used it, I recommend researching its potential benefits as it is said to be an improvement.
I may not have personal experience with it, but I am facing a similar situation. My AMH levels are slightly elevated, but I do not have any other signs of PCOS or symptoms. During my egg retrieval, I was able to retrieve a good number of eggs with a high fertilization rate and minimal chromosomal issues. Metformin has been prescribed to me due to recurrent losses on IVF cycles. I am interested in hearing from others who are in a similar situation, and would appreciate any shared experiences.