I’ve been wrestling with this decision lately, and I’m hoping to get some advice from those who have experience with either progesterone injections or suppositories. I’ve heard arguments for both sides, with some praising the convenience of suppositories while others swear by the effectiveness of injections.
Personally, I’ve been leaning towards the injections for better absorption, but the thought of the daily injections is a bit daunting. On the other hand, the suppositories seem easier to administer but I’m not sure if they’re as effective.
Have any of you tried one or the other? What was your experience like? I would greatly appreciate any insights or personal anecdotes you can
I don’t mind the discharge from the suppositories because I’d rather have that than a needle in my behind. My doctor mentioned that in modified natural cycles, injections aren’t necessary since our bodies produce progesterone naturally. We just need some extra support.
I am currently going through a transfer cycle using both PIO injections and suppositories. If you’re interested, I can share my experiences with both. While I am amazed by those who can self-administer the PIO shots, I personally can’t do it and rely on my husband for this task. The injections have left me with some bruising and soreness.
On the other hand, I have to follow a strict schedule for the suppositories, set by my phone alarm every 6-8 hours. It’s a hassle to manage this while at work, especially with the messiness involved. I find the constant need to change liners unpleasant and uncomfortable. Although my clinic says it’s safe to have intercourse while using these suppositories, I have reservations due to the six pills I have to insert daily.
I have done 1 modified natural cycle with suppositories and 2 medicated cycles with PIO injections. I find that I prefer the injections. The pros of the injections include once-a-day dosing and fewer symptoms. On the other hand, using suppositories requires 3 times a day dosing, can be messy, and may cause irritation. Once you establish a good routine with injections, such as heating, massage, and finding the right spot, it becomes quite manageable.
I am using pessaries and suppositories instead of pio shots because my body couldn’t handle them. I had to take 6 shots daily before my FET, and it took 20 days for all the lumps to go away completely. Currently, I am using a combination of aqua-based injections, pessaries, and oral medication.
I usually opt for PIO instead of suppositories in a modified natural cycle because I find them messy, itchy, and smelly. Despite the challenges of PIO, I have experimented with different methods to make it less painful and more manageable.
I initially had reservations about receiving regular IM injections, but now I am doing them every other day as part of my modified natural FET and it has been going smoothly. I also use BID suppositories without any issues. The discharge is not bothersome and there have been no other problems. In modified natural cycles, the emphasis is on letting your body do the work with supplementation based on lab results. I was advised that it doesn’t matter whether I use suppositories, PIO, or both as long as the combined treatment meets the desired threshold. I decided to include the injections because it provides reassurance in maintaining appropriate levels.
I prefer shots because some doctors warn that missing a supplement dose can have negative consequences. I found it inconvenient and risky to have to pull down my pants in my car to insert a suppository.