Sharing My Experience: Prednisone and IVF

I recently started my IVF journey, and one of the medications prescribed by my doctor is prednisone. I’ve been reading mixed information about the use of prednisone during IVF treatments. Some sources say it can improve implantation rates, while others mention the potential side effects. I would love to hear from others who have used prednisone during their IVF cycles. Did you notice any differences in your outcomes or experience any side effects? Any insights or personal stories would be greatly appreciated! Let’s share and support each other through this process.

After only one unsuccessful transfer, there is limited evidence. I have had five transfers and took it last time, but still failed and felt terrible.

I am following the Bondi protocol with a customized natural approach. Taking 20mg of prednisolone daily and feeling quite terrible on it. Due to family history of autoimmune issues, decided to try this after two euploid failures. Will update on my progress soon.

My doctor suggests this medication for my endometriosis. I started at 10 mg and decreased to 5 mg, but have not seen any improvement so far.

Adding prednisone, along with Claritin and Pepcid, resulted in successful pregnancies after facing a miscarriage with a euploid embryo. I had four live births in the following eight transfers without any further losses. Although I can’t be certain, I believe this protocol played a role in my successful outcomes.

I had 5 failed IVF attempts and an ectopic pregnancy before my successful transfer. I took all the medications prescribed by CNY, including prednisone, and gave birth to my baby 6 weeks ago. It’s hard to say which treatment was the most helpful. Prednisone was the only medication that gave me side effects, causing weight gain and puffiness in my face. However, it made me feel great, which made me consider if I have underlying autoimmune issues. Despite getting Covid shortly after my transfer, I still believe in the effectiveness of CNY’s protocol for recurrent loss. Research in this field is challenging due to various root causes and the complexity of pregnancy. Different treatments may work for different individuals, making it difficult to draw definitive conclusions. It’s important to critically analyze research findings before making decisions about treatment options.

There are many factors to consider when evaluating the benefits of prednisone, making it difficult to attribute success or failure solely to this medication. I chose not to take prednisone due to the lack of strong evidence supporting its effectiveness and concerns about potential negative impacts on the immune system.

Despite having a diagnosed autoimmune condition, my doctor advised against taking it due to lack of evidence. He believes that an immune response is necessary for implantation to occur and is against suppression. However, some doctors see it as a “can’t hurt, might help” situation.

Does your husband work as a reproductive endocrinologist?

I am currently tapering off after a failed FET and it is really tough. I am going through a period of emotional and physical recovery. I find myself needing to take a nap every afternoon and feeling very sluggish.

The first three transfers resulted in early losses, with two chemical pregnancies and one blighted ovum. My reproductive endocrinologist suggested trying a comprehensive immune protocol for the next transfer, which ultimately led to success. I was prescribed prednisone 10mg once daily, along with lovenox, pepcid, and claritin.

I mistakenly only took 5mg of the prescribed medication for the entire duration, believing it could potentially help with my allergies and other benefits I might receive from taking it. I have since stopped taking it.

I have found that taking 20mg-30mg at transfer time is effective for me. I consult with a reproductive immunologist for guidance.

I highly recommend looking into anti-inflammatory and immune system protocols as they may help with fertility issues. Your doctor is knowledgeable and trustworthy in guiding you through this process.

I am presently taking 5mg twice a day and plan to gradually reduce the dose this week. I have a history of autoimmune disease. My doctor suggested trying this treatment as it may have benefits. I decided to give it a try as I wanted to explore all options and avoid any regrets. Additionally, the low dosage did not cause me any noticeable side effects.

My doctor instructed me to take this medication twice daily.

This is also included in our standard protocol.