In summary, while the post is generally excellent, it contains one key error regarding the detection of HCG in urine. The key factor in detecting HCG is the concentration of the urine, not the volume at the time of voiding. The most concentrated urine is typically second morning urine (SMU), especially if no liquids have been consumed after the first morning urine (FMU). This concentrated urine provides the best environment for accurate testing. Holding urine overnight, as suggested in the post, is actually counterproductive as it dilutes the urine with less concentrated components. In essence, testing with SMU after a period without consuming fluids is the most effective method for detecting HCG levels.
This information was helpful, but I am struggling with the assumption that a positive test would occur the day after implantation. Based on research by the same authors on the same population, it appears that 50% of women may not reach the necessary hCG levels for a positive test until 6-7 days after implantation, rather than the 1-2 days assumed in the original post. This suggests that even with implantation on 3 days past a 5-day embryo transfer, there is a high likelihood that a positive test on a FRER may not occur until 9 days post transfer. I am unsure of how to accurately interpret the mean values provided in the paper in terms of the percentage of women who may not test positive until certain days post implantation, and I am seeking clarification from someone experienced in reading scientific papers. Based on my calculations, is it correct to say that a person in the lower 50th percentile would need to test at 9 days post transfer for a 13% miscarriage rate, 10 days for a 26% rate, and 11 days for a 52% rate?
I completely disagree with this.
Thanks for the update! Today marks 5 days past a 5-day embryo transfer, and after taking a test, I noticed a faint second line.
I never considered this perspective before. I have never tested early because I am aware that many pregnancies at the earliest stages do not continue, so a positive result on test day indicates that it has passed a significant hurdle. Although it is difficult for me to wait, I believe it would be even harder to receive a positive result and then have it disappear. I would prefer to receive a negative result a few days later instead. However, the timing of testing is a significant concern for individuals undergoing IVF, and it is largely overlooked at my clinic. Thank you for sharing your insight.
I’m wondering if the study in question involved embryos that were tested using PGT. Our embryo was not tested, but based on my positive test results on day 6, I believe it implanted between days 3-4. I was too nervous to test on day 5, but I’m confident that it would have been positive based on the strong line on day 6. I also experienced implantation twinges in my right lower belly 12 hours post-transfer, which still persist. I’ve heard this is common in my family. I’m trying to ease my worries about the success of a non-tested embryo. If anyone has information on the study, I would appreciate it. Thank you!
If you are currently awaiting results from your FET, please be aware that the study mentioned in the link pertains to women without fertility issues who are not on hormones. It does not necessarily apply to FET timelines. For FET, implantation and testing days may not align with DPO. Stay patient and don’t get discouraged if you haven’t tested positive by day 6.
I wish I had more upvotes to give you! Great job!
I am currently 6 days past a 5-day embryo transfer and I took a test midday, which showed a negative result. I understand that it is recommended to take these tests in the morning, but I wanted to try it anyway. I am very well-hydrated, to the point of clear urine. Is there a chance that the test could still be positive despite my hydration levels, or should I accept the negative result and prepare for another round of treatments with needles? This was our only frozen embryo.
Question for anyone who can clarify: Does 5DP5DT refer to the 5th day after the transfer, meaning that the first day is the day after the transfer and not the day of the transfer itself? Thank you!
Is it justifiable to extend the timeframe for 3-day transfers by two days, or should we take into account other variables? More specifically, would this increase our chances of achieving a 76% accuracy on FRER at 7dp3dt, 96% accuracy at 9dp3dt, etc.? (Note: It is important to consider that the miscarriage rate may not be directly comparable as many individuals opt for 3-day transfers due to additional risk factors.)
I just wanted to express my gratitude for your post. It was incredibly useful to me three years ago when I used a FRER test with light pink caps and received a positive result on 4dp5dt, leading to a successful live birth. However, it appears that the new FRER tests with dark pink caps may not be as sensitive. Do you have any information on the sensitivity of these tests and whether we can still trust this method for accurate results?
I found this information to be extremely beneficial! I appreciate your effort in conducting the research and presenting it in such a clear manner for everyone to understand.
My previous transfer resulted in a positive test on 8DP5DT, but unfortunately, it turned out to be a chemical pregnancy. This article has helped me manage my expectations. I am currently on 7DP5DT with my next transfer and still receiving negative results, so I am preparing myself for the possibility of another disappointment.
I have passed this information along to numerous individuals and wanted to thank you for it. I followed the advice precisely, and it proved to be extremely beneficial.
Hello, I wanted to ask if anyone has information on the sensitivity differences between the light pink and dark pink caps on FRER tests. Some people online are saying that the light pink cap is more sensitive, but I have only been able to find tests with dark pink caps in stores and online.
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I appreciate your clear and helpful explanation.
Thank you for starting this thread, as it has been quite helpful. We underwent a 5-day frozen embryo transfer last Monday afternoon, using a grade 1 embryo with a lining measuring above 9 (29 years old female). Today, we received a negative test result. Although the blood test is scheduled for Saturday, we are mentally preparing for the likely possibility that the transfer was unsuccessful.
Wow, what an amazing post. I appreciate it!
This has been extremely beneficial.
I have been relying on extremely inexpensive pregnancy test strips, and I suspect that the faint lines I am seeing are just evaporation lines that appear after the recommended time frame (which is before 10 minutes). I am currently 8 days after my frozen embryo transfer. My blood test is scheduled for the Wednesday before Thanksgiving, and we are hosting our family for the holiday. I want to address my emotions before they arrive. It seems likely that I will receive a negative result. I haven’t given up hope, but I want to be psychologically prepared in case the news is not what I had hoped for.